Main area HSCT and Cellular Therapy Grade NHS AfC: Band 7 Contract Permanent: Home working Hours Full time - 37.5 hours per week (May accept 30 hours) Job ref 196-LIS9678

Employer Guy's and St Thomas' NHS Foundation Trust Employer type NHS Site Homeworking, but our registered office is Town London Salary £54,320 - £60,981 per annum Salary period Yearly Closing 27/07/2025 23:59 Interview date 08/08/2025

Guy’s and St Thomas’ is among the UK’s busiest and most successful NHS foundation trusts. We provide a full range of hospital and community services for people in south London and as well as specialist care for patients from further afield including cancer, renal, orthopaedic, respiratory and cardiovascular services.

Guy’s is home to the largest dental school in Europe and a £160 million Cancer Centre opened in 2016. As part of our commitment to provide care closer to home, in 2017 we also opened a cancer centre and a kidney treatment centre at Queen Mary’s Hospital in Sidcup. St Thomas’ has one of the largest critical care units in the UK and one of the busiest emergency departments in London. It is also home to Evelina London Children’s Hospital.

Evelina London cares for local children in Lambeth and Southwark and provides specialist services across south east England including cardiac, renal and critical care services. We lead a number of specialist service networks aiming to ensure children are treated locally where possible, but have access to specialist expertise when they need it. Our community services include health visiting, school nursing and support for families of children with long-term conditions.

Our adult community services teams deliver care at the heart of the local communities we serve, working in partnership with GPs, local authorities and other healthcare and voluntary sector organisations. Working with our partners in Lambeth and Southwark, we are focusing on new ways of working to improve care for local patients.

In February 2021 the Royal Brompton and Harefield joined Guy’s and St Thomas’ NHS Foundation Trust, bringing together world-leading expertise in the care and research of heart and lung disease. Our merger provides a once in a generation opportunity to build a lasting, world-renowned heart and lung centre, providing the highest quality care for patients and conducting world-leading research.

We have a reputation for clinical excellence and high quality teaching and research. We are part of King’s Health Partners, one of eight accredited UK academic health sciences centres. In partnership with King’s College London we have dedicated clinical research facilities including an MHRA accredited Phase I clinical trials unit.

Patients are at the heart of everything we do and we pride ourselves on ensuring the best possible patient experience as well as safe, high quality care. We are proud to have one of the lowest mortality rates in the NHS. Following a comprehensive Care Quality Commission (CQC) inspection in 2019 we maintained our overall rating of ‘good’. Our adult community services achieved a rating of ‘outstanding’.

The commitment of our 23,500 staff is key to our success. We are one of the largest local employers and we aim to develop and support all our staff so they are able to deliver high quality, safe and efficient care. The 2019 NHS staff survey results show that we have one of the most engaged and motivated workforces in the NHS. We know this has a positive impact on the care provided to our patients.

We have one of the most ambitious capital investment programmes anywhere in the NHS.

Job overview

Could you be passionate about making a significant contribution towards ensuring that leukaemia, lymphoma, aplastic anaemia, and immune deficiency disorder patients receive the highest-quality and most effective treatments and care they need to live well?

The British Society of Blood and Marrow Transplantation and Cellular Therapy (BSBMTCT) has an exciting opportunity for an enthusiastic and committed Senior Medical Statistician, who will lead the statistical work of our Society and data registry.

You will provide full statistical support and analysis to meet a range of purposes including research, the statutory reporting of outcomes of stem cell transplants and other cellular therapy treatments, and the meeting of our contractual obligations to commercial partners, which generates income towards the achievement of our mission. As our partnerships become established, we anticipate that you will oversee the work of a small team of statisticians, working across partner organisations. You will work closely with the Trustees, Chief Executive, Head of Registry, data management team, sub-committees, members, investigators and commercial partners.

Our staff are hosted by Guy’s and St Thomas’ NHS Foundation Trust and enjoy the benefits of being an NHS staff member, whist focusing upon improving patient outcomes – both survival and quality of life - by advancing the fields of blood and marrow transplantation and cellular therapy.

Main duties of the job

You will work with the Trustees, Chief Executive, Head of the Registry, the data management team, Sub-Committees, including the Clinical Trials Sub-Committee (CTSC), individual members, investigators and commercial partners to lead our statistical work and provide full statistical support and analysis to meet a range of purposes including:

· the statutory reporting of outcomes of stem cell transplants and other cellular therapy treatments

· meeting our contractual obligations to commercial partners, generating income for BSBMTCT, for application across the wider BMTCT community

You will work with key investigators involved in complex studies which have been peer reviewed and approved by the BSBMTCT CTSC. Close liaison with the Co-Chairs of the BSBMTCT CTSC, and the Head of the BSBMTCT Data Registry will be required.

You will be required to review all study proposals from the outset and, in liaison with the Head of the BSBMTCT Data Registry, advise on feasibility of any protocols submitted for review.

This role will, in time, supervise a small team of statisticians and data analysts/scientists, working directly or within one or more partners. The BSBMTCT team works with a wide range of medical professionals across the country and in Ireland and collaborates with clinicians across Europe and the world.

Working for our organisation

The British Society of Blood and Marrow Transplantation and Cellular Therapy (BSBMTCT) is the professional society for bone marrow/stem cell transplant centres in the UK & RoI. We have 49 NHS and private member centres contributing data to the registry. The BSBMTCT Registry was established in March 2001 and is the UK Subset of the European Registry for Blood and Marrow Transplantation (EBMT).

Our purpose is to improve patient outcomes – both survival and quality of life - by advancing the fields of blood and marrow transplantation and cellular therapy.

We strive for a worldwhere all transplant and cellular therapy patients receive the highest-quality and most effective treatments and care they need to live well. This is our vision.

Our Mission is to:

• Serve as the representative voice and advocate.
• Maintain a registry of all stem cell transplants and cellular therapies in the UK and RoI, and provide data and insight to inform research, commissioning, policy and clinical practice.
• Undertake, facilitate and contribute to pioneering research and clinical trials that improve the outcomes of treatment and care.
• Provide education and training to transplantation and cellular therapy professionals, promotinh the sharing of knowledge and good practice.
• Develop guidelines, protocols and quality standards
• Provide data and insight to patients and the public, to educate and empower them as they make decisions about their treatment and care.

Detailed job description and main responsibilities

Provide effective leadership and specialist statistical expertise to the wide-ranging work of the British Society of Blood and Marrow Transplantation and Cellular Therapy (BSBMTCT).

Facilitate research from accrued study data, undertaking the required data analyses with a view to publication in peer reviewed scientific journals.

Project manage statistical research projects and other BSBMTCT projects as required to meet BSBMTCT’s business plan and other key work objectives.

Oversee the provision of feasibility reviews on potential new studies, both retrospective and prospective, being proposed by the BSBMTCT CTSC, including the recommendation of appropriate cohort sizes and structures of studies, so as to maximise their scientific integrity.

Assist with the reporting of studies and writing of papers for publication in peer reviewed, nationally and internationally read journals, with emphasis on the statistical aspects of such papers.

Communicate statistical/analytical/epidemiological matters clearly to data managers, statisticians, clinicians, nurses. other allied health professions and very senior colleagues.

Provide, receive, interpret and communicate very complex information in a way that is easily understandable and carries people along with you.

Communicate effectively the results of complex analyses to a range of stakeholders including individuals, and small and large groups.

Collaborate with national and international registries and bodies (especially NHSE and the other national NHS bodies) and international and global bodies such as CAN/UK/ANZ (partnership between Canada, Australia, New Zealand, and the UK) and EBMT, the European Group for Blood and Marrow Transplantation, based in Leiden and Barcelona.

Responsibility for effective line management and support, including assigning responsibility for individual tasks, providing day to day support and balancing the workloads of individuals, appraisal, staff development, staff motivation, work plans, training and supervision of other staff as required.

Management and co-ordination of work flow with Statistician’s who work on our behalf for external organisations.

Responsible for engaging with pharmaceutical companies and other commercial partners to understand their requirements and deliver against agreed contracts.

Person specification

Qualifications

• Degree or equivalent level qualification in Statistics/Mathematical or Biomedical Sciences or an allied subject (including health care disciplines)
• Masters level qualification in medical statistics, applied statistics or in a related healthcare/mathematical discipline

Experience

• Extensive operational experience in highly complex statistical analysis in a clinical environment
• Experience of using statistical methods and the essential preparation required to ensure clean data prior to conducting any analyses
• Experience of working with large sets of very large and highly complex data
• Experience of providing, receiving and interpreting very complex and contentious information

Skills/Knowledge

• Familiarity with the use of database tools to input, generate reports and analyse the data
• Proficient user of MS Word, Excel, PowerPoint and e-mail, and a willingness to learn new systems/familiarity with Stata or SPSS or R
• Excellent interpersonal skills to facilitate liaison with colleagues and study collaborators across the UK and Republic of Ireland
• Evidence of an awareness of statistical thinking, techniques, and current literature
• Able to analyse highly complex data, compare possible interpretations of the data and present a judgement of the correct interpretation
• Able to plan and organise workload on multiple and competing studies and to meet deadlines for submission of abstracts for conferences, revision of manuscripts for journals, and other external presentations
• Ability to advise on the planning of studies – both ongoing and proposed and to explain statistical concepts and findings to all levels of audience
• Ability to recommend cohort size, structure and data collection requirements of studies

General

• Recognise ethical and legal issues involved when dealing with and safeguarding confidential patient data
• Willingness to travel to attend meetings and conferences

Guy’s and St Thomas’celebrates, respects and values the diversity of its staff and patients. We review our policies, procedures and practices to ensure that all employees, patients and carers are treated equitable according to their needs. We are actively committed to ensuring that no one who applies for a job, works or study’s at the Trust, or accesses our services is discriminated against on the grounds of race, ethnicity, nationality, disability, religion or belief, age, gender identity , gender reassignment, sexual orientation, pregnancy and maternity/paternity, or marital/civil partnership.

Applications are welcomed from applicants with a disability. We can make reasonable adjustments and offer support and advice in a variety of ways throughout the application process. Equality of opportunity is our policy.

As an organisation we are committed to developing our services in ways that best suit the needs of our patients. This means that some staff groups will increasingly be asked to work a more flexible shift pattern so that we can offer services in the evenings or at weekends.

We are committed to supporting all employees to achieve a healthy work life balance and to work in a way that is best for them and our patients. We will consider all requests to work flexibly, taking in to account the individual’s personalcircumstances as well the needs of the service. We encourage all prospective applicants to discuss their individual circumstances with the recruiting manager as part of the on-boarding process.

Your e-mail address is important to us -We communicate to all job applicants via the e-mail address which has been provided on the application form. Please ensure that you check your e-mail on a regular basis.

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